Right on TARGET: glutamine metabolism in cancer

نویسندگان

  • Boris Ratnikov
  • Young Joo Jeon
  • Jeffrey W. Smith
  • Ze'ev A. Ronai
چکیده

Recent studies highlight the importance of glutamine metabolism in metabolic reprogramming, which underlies cancer cell addiction to glutamine. Examples for the dependence on glutamine metabolism are seen across different tumor types as during different phases of cancer development, progression and response to therapy. In this perspective, we assess the possibility of targeting glutamine metabolism as a therapeutic modality for cancer.

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عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2015